The Giant Mouse of Minsk is a fictional mouse from the An American Tail series.
The Giant Mouse of Minsk is only mentioned in An American Tail. Papa Mousekewitz claims that it is a mouse that was as tall as a tree and had a mile-long tail. Though it is never actually seen, a mechanical version of the mouse is made by the mice of New York led by Gussie Mausheimer and Honest John out of things that they found in an abandonded museum. It was used as the mice's "secret weapon": a mechanical mouse equipped with 4th of July firecrackers and colorful rockets. It sends the Mott Street Maulers running away and onto a tramp steamer bound for Hong Kong and ends up at the bottom of the waters around Chelsea Pier. It is apparently a well-known legend, as Warren and Digit were well aware of it before being driven off the pier.